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Facility Services Division

All licensing fees must accompany the completed application form and be mailed to the following address:

Financial Management - Receipting Unit
Oklahoma State Department of Health
PO Box 268823
Oklahoma City, OK 73126-8816

Failure to do so may result in a delay in the processing of your license application.

Information and Resources

  • Hospitals 
    • General Medical Surgical Hospitals; Critical Access Hospitals and other Specialized Hospitals: Psychiatric, Rehabilitation
    • Oklahoma licensure of hospitals is required by Title 63, Oklahoma Statutes, Sections 1-701 et seq; Oklahoma Administrative Code (OAC) Chapter 667
    • Oklahoma licensure of Rural Emergency Hospitals is required by OAC Chapter 667 Emergency Rules
    • Recent legislation
      • HB 3644, The Blake Burgess Act: Effective July 1, 2026, this bill requires hospitals with an emergency department and ambulatory surgery centers to develop and implement policies and procedures to ensure appropriate medical attention for persons at risk of forming venous thromboembolisms, assisting patients at risk, treatment options, and training all non-physician personnel at least annually on policies and procedures developed for this purpose.
      • SB 1423: Effective Nov. 1, 2026, this bill eliminates the Hospital Advisory Council.

* These facilities do not have licensing requirements for Oklahoma and require Certification by The Center for Medicare & Medicaid Services.  

To learn more, visit Clinical Laboratory Improvement Amendments of 1988 (CLIA)

Phone: (405) 426-8470
Fax: (405) 900-7559
Emailclia@health.ok.gov

  • CLIA has transitioned to sending email notifications to laboratories to include electronic CLIA fee coupons and certificates. Paper fee coupons and certificates are no longer available. Fee coupons and links to certificates will be emailed to the email address on file for the laboratory and come from “Center for Clinical Standards and Quality” or from noreply-cms-ccsq@ccsq.hhs.gov.
  • Fees can be paid online using ACH transactions, debit or credit card 

  • Email: clia@health.ok.gov
  • Fax: (405) 900-7559 
  • Mail:
    Oklahoma State Department of Health
    Medical Facilities/CLIA
    123 Robert S. Kerr. Ave Suite 1702
    Oklahoma City, OK 73102-6406

  • A link to print your new CLIA certificate will be emailed approximately 2-3 weeks prior to your certificate expiration date or within 10-14 days for an initial certificate.

  • Submit your request to change the director on your CLIA certificate on the CMS-116
  • All 5 pages must be filled out completely and signed. 
  • The form can be emailed to CLIA@health.ok.gov or faxed to (405) 900-7559. 
  • If you have any questions, please contact us via email or at (405) 426-8470.

  • Email clia@health.ok.gov and provide the CLIA number, laboratory name on the certificate, and email address.

Contact Information

Mailing Address:
Oklahoma State Department of Health
Medical Facilities Service - Facility Services Division - CLIA
123 Robert S. Kerr. Ave Suite 1702
Oklahoma City, OK 73102-6406

Phone: (405) 426-8470
Fax: (405) 900-7559

Emailmedicalfacilities@health.ok.gov
Email: CLIA@health.ok.gov